The final episode made it clear they didn't really win the lottery, so there's no need to ignore that part.
Actually, it didn't, depending on which way you are looking at it. The [then] series finale made it clear there were two unvierses: the fake one we saw for several seasons in which they won the lottery and Dan stayed alive, and the real one we never saw that the Roseanne character talked about in the closing approx. ten minutes of the finale, where Dan did die and apparently -- by the looks of her writer's room -- they aren't as poor as they were in the series.
The Roseanne character talked about what the real universe was like:
* Leon was not as cool as I made him to be.
* Scott (Leon's husband in the fictional Roseanne universe, or the show) was a probate lawyer and she introduced Leon to him.
* Her mother was not gay and was submissive as a wife.
* Jackie was really gay.
* Nancy found a great spiritual awakening.
* Becky and Darlene's husband's at the end were switched.
* Real verse Dan died when he had a heart attack.
So, it depends on how they are going to approach the series; are they going to go with the fake universe her character created where they won the lottery* and Dan stayed alive or the real one we never saw. They say Dan faked his death, so that means they are going with the real life we never saw, however I am wondering if they are confusing things and forgotten the whole Roseanne voiceover from the series finale, 'cause that would mean dropping the entire series of established loved characters, backgrounds, events, and supplant it with new ones we never saw.
* = I say won the lottery, but really, as the show showed, they blew it all and ended broke in the fake universe; she gave the local factory the amount she won and on top of that there was all the spending they did on various things including improving the inside of the house, so the fake universe characters were in debt. They looked awfully happy about it; no doubt the show writers simply didn't realize what they did.