I'm a big FF fan (have issues #13 - 180 of the original comic still - 180 is when I stopped reading comics in general) - and I know the Ultimate FF origin story (which is more what this film appears to be using) - but yeah, after seeing the trailers, and the other major change to Johnny Storm (an d now Due's 'adopted', etc.) - I have ZERO desire to see this film. Hell, this time the Thing is 100% CGI, but has virtually NONE of the classic 'Thing' look from the comics.
I also never cared for the 'Ultimate' storyline change making Reed, Sue and Ben near teenagers. Again, that may not be FOX's doing, but I never liked what it did for the team dynamic myself. I've also never cared for the 'Ultimate' version of Victor Von Doom either.
This one's probably going to bomb bigger than FOX's first two attempts and we'll never see the FF again until/unless Marvel Studios somehow reacquires the film rights. IF that happens I pray they won't go with the 'Ultimate' versions, but we'll see. Again most likely this will be the last attempt at a big budget FF film.