BTW, since when was Mr. Sinister a man that experimented on himself? When I last read X-Men, he was made that way by Apocalypse. That's why he was trying to create a being like Cable to kill Apocalypse, so he could be free. When did this change?
In the comics he was made by Apocalypse, though that wasn't his intended origin (he was supposed to be a nigh-immortal mutant trapped in the form of a 10 year old boy, so that boy created Sinister as his "projection". it's why Sinister looks like something out of a kids nightmare).
In the 90s cartoon they simplified his origin by having him turn himself into a mutate without Apocalypse.