Another interview about what we will and won't get answered:
Damon gave us a sense of what kind of Lost questions will be answered, and which other mysteries won't explicitly be explained by the end of the series: "There are certain questions about the show that I'm very befuddled by like, 'What is the Island?' or 'What do the numbers mean?' We're going to be explaining a little more about the numbers, maybe significantly more about the numbers, but what do you mean by 'What do the numbers mean?' What is a potential answer to that question? I feel like you have to be very careful about entering into midi-chlorian territory...I grew up on Star Wars, I've seen the Star Wars movies hundreds of times, I can recite them chapter and verse, and never once did anyone ever say to me or did it occur to me to say, 'What is the Force, exactly? Can you explain that for me, better than Alec Guinness does?' I understand, 'When are we going to find out about Libby?' That's a very finite question. 'Who is Jacob?' OK, yes, we've been talking to this guy named Jacob, so those questions then should have answers, but 'What is the Island?' That starts to get into 'What is the Force?' It is a place. I can't explain to you why it moves through space-time, it just does. You have to accept the fact that it does." Can you live with that?
And:
[/I]Libby's story will not be wrapped up on the show. Says Damon, "I have learned that if you kill someone off the show, they are less likely to cooperate with you." Basically, Cynthia Watros is busy until further notice and they can't explain Libby without her, at least not in any way that shows her story rather than annoyingly tells her story. What's the takeaway for us fans? Next time you've got Damon cornered, don't waste your breath asking about Libby. Instead, bust his chops about another very important blonde: Claire! Where is that little minx, anyway?