From the "we dodged a bullet department", we've nearly had American James Bonds on numerous occasions. both Burt Reynolds and Adam West were considered for Bond in the late 60s. West reportedly turned it down because he thought Bond should be played by a British actor, and I'm not sure why Reynolds said no. Although these have the makings of "urban legend" as with Reagan and Casablanca, both have actually been confirmed by various Bond-related sources and Reynolds was interviewed about nearly becoming Bond last week in conjunction with his appearance on Archer.
An American actor you've never heard of named John Gavin was signed to play Bond in Diamonds Are Forever, but was let go when Connery agreed to come back. Similarly, James Brolin (yes, Mr. Barbara Streisand) was either signed or almost signed to play Bond in Octopussy but Roger Moore agreed to come back.
One wonders how Reynolds' career, in particular, would have developed if he'd taken the role of Bond. Would he have gone on to become a symbol of the "good ol' boy 70s" with his Smokey and the Bandit movies? Would Cosmo have had its biggest selling issue ever?
If Adam West had taken the role, would that have allowed him to escape the typecasting left behind from Batman?
I personally can't imagine how an American Bond would have turned out.
(Well, I guess yes I can:
http://www.youtube.com/watch?v=5bBnVDj5SkA )
Alex