I had some ideas of my own, but after reading this thread, I have to back the Gor-plants idea. I see David Chase as showrunner, adding the same kind of surrealist touch he did for that dream with the fishes.
Beyond that I'm mostly stumped. I can think of plenty of sci-fi novels I'd like to see as movies, or perhaps miniseries, but multi-season TV shows becomes a much shorter list - probably because I simply haven't read a lot of serialized sci-fi. Not that I haven't read a lot of sci-fi over the years, but it's almost always been self-contained narratives rather then a sprawling universe you could spend 80 odd episodes in.
Other people, obviously, have read such books, and I'd be quite interested in seeing TV series based on those books - if nothing else as the final prod for me to bother to get around to reading them (which was my belated excuse for checking out the torturously titled
A Song of Ice and Fire series).
Screw it, let's get a miniseries, let's call it
Valis, and if they still have Paul Giamatti's number from back with
John Adams, then we have our Horeslover Fat.
Or I don't know... try fashioning the Hainish Cycle as a TV series. I just know
Left Hand of Darkness is the best sci-fi book I've read in years.
I vote for not going to happen. "Game of Thrones" works because
1. Fantasy is artistically pretentious aka you get out of work British actors running around in chain mail and it looks good.
HBO has been willing to do very weird, mind. I'm thinking of
Carnivale here. Certain kinds of weird have a degree of TV critic cred, and that includes mind-bending material one could easily grab from some sci-fi books... see
Valis, above.
Element of truth here though, which is arguably shadowed by the most HBO-ish of science fiction TV shows, Ron Moore's
Battlestar Galactica. That show largely eschewed outre costuming or alien makeup in favour of a quasi-military pseudo-realism that at first brush isn't that different from
Game of Thrones playing up its pseudo-medieval period-ness.
I think any HBO sci-fi series is likely to take itself as seriously as that, and seriously doubt we'd get something as gleefully wonky as
Farscape.
On the other hand, part of HBO's brand is taking genres and playing around with them a little - the Western, the cop show, and now fantasy.