I don't care how good they are, there are many genres, topics and settings that will insure I will NEVER watch a particular show or movie. I actually don't watch that many movies, so don't be surprised that my list rules out most of what is made today:
1. superheroes
2. mafia or crime/police drama
3. medical drama
4. westerns (with the notable exception of Deadwood)
5. horror {"suspense" is ok)
What is your list?
1. "Butt kicking action babe" shows. Dollhouse, which at least had other interesting characters, is the last time I put myself through that crap.
2. Sitcoms with useless male characters.
3. Shows about good looking American teenagers, usually featuring a token, permanently cock-blocked nerd character who they all like "as a friend".
4. "Romantic" comedies. Not sure what's so romantic about a guy changing every aspect of his personality in order to fit what some woman wants.
5. Anything to do with fashion.
6. Although I used to watch all three - the CSI shows. They seem to spend most of their time judging the people they're investigating rather than gather evidence.