The main thing I'd be concerned with about using server-grade hardware is cooling. Servers tend to sound like bloody jet engines because they're expected to be put into a data centre with giant aircon units where people don't actually work and have loud-ass fans inside them on top of it. I can't say I'd want something like that running in my flat.
That's due often to the cases which sees servers in an in 1 and 2RU rack mount cases whch requires them to use 1" fans which do scream like banshees.
Also with the the current CPUs like the i7s they need just as much cooling.
Put the board into a quality tower case with 120mm fans and it will be much quieter.