Skipping over the nonsense defending 1984 (and the few remarks that weren't, too,) the list suffers from the usual input from young people who only know the new stuff, or a handful of officially approved books fed to them by school reading lists. That's to be expected to a certain degree but really even a young person should be able to distinguish the movie and the novel. Do Androids Dream of Electric Sheep? is not Blade Runner.
Personally I find mixing the SF and fantasy rather undiscerning.
1. The Lord Of The Rings Trilogy, by J.R.R. Tolkien
If you insist on fantasy, at least this is a good one.
2. The Hitchhiker's Guide To The Galaxy, by Douglas Adams
Not my first thought, but humor is underrated. This is an example of how these little games with the lists can be rewarding.
3. Ender's Game, by Orson Scott Card
Every fifteen year old's favorite SF novel. Pity I wasn't fifteen when I tried to read it.
4. The Dune Chronicles, by Frank Herbert
Chronicles, chronicles? WTF? Just Dune, please.
5. A Song Of Ice And Fire Series, by George R. R. Martin
See what I mean about distinguishing the movie and the book?
6. 1984, by George Orwell
Who says high school English teachers have no influence?
7. Fahrenheit 451, by Ray Bradbury
I would put it on the list but I'm not ashamed to admit I was influenced by my high school education.
8. The Foundation Trilogy, by Isaac Asimov
Justifiably high
9. Brave New World, by Aldous Huxley
Not just on the reading lists but still relevant.
10. American Gods, by Neil Gaiman
There was a brilliant short story about Pan (by Lester Del Rey) that made this novel unreadably familiar and bloated.
11. The Princess Bride, by William Goldman
Again, humor is underrated. If you must have fantasy, an instructive choice.
12. The Wheel Of Time Series, by Robert Jordan
Is this even finished? How would anyone know yet?
13. Animal Farm, by George Orwell
No one was foolish enough to rush to the defense of this one, but an attack on the Russian Revolution that covers up the Great War is abominably dishonest.
14. Neuromancer, by William Gibson
15. Watchmen, by Alan Moore
16. I, Robot, by Isaac Asimov
17. Stranger In A Strange Land, by Robert Heinlein
Could this novel be good for anything but opening the eyes of painfully naive adolescents in repressive societies?
18. The Kingkiller Chronicles, by Patrick Rothfuss
Who?
19. Slaughterhouse-Five, by Kurt Vonnegut
20. Frankenstein, by Mary Shelley
Again with the movies. Very few people really like the novel, they can't be bothered with the eighteenth century style.
22. Do Androids Dream Of Electric Sheep?, by Philip K. Dick
Another movie tie-in.
23. The Handmaid's Tale, by Margaret Atwood
24. The Dark Tower Series, by Stephen King
Are they serious?
25. 2001: A Space Odyssey, by Arthur C. Clarke
Yet another movie tie-in.
26. The Stand, by Stephen King
27. Snow Crash, by Neal Stephenson
Is this the one that starts with people alive today living long enough to start imitating the Victorians? I've always found Neal Stephenson tough to plow through.
28. The Martian Chronicles, by Ray Bradbury
29. Cat's Cradle, by Kurt Vonnegut
30. The Sandman Series, by Neil Gaiman
31. A Clockwork Orange, by Anthony Burgess
32. Starship Troopers, by Robert Heinlein
32. Watership Down, by Richard Adams
33. Dragonflight, by Anne McCaffrey
Ugh.
34. The Moon Is A Harsh Mistress, by Robert Heinlein
35. A Canticle For Leibowitz, by Walter M. Miller
Underrated
36. The Time Machine, by H.G. Wells
37. 20,000 Leagues Under The Sea, by Jules Verne
Yet another movie tie-in, or lots of James Mason fans.
38. Flowers For Algernon, by Daniel Keys
Yet another movie tie-in. Nobody much read the novel, everybody loved the short story, as they should have.
39. The War Of The Worlds, by H.G. Wells
This should have been at #6, vastly more relevant to today's world.
40. The Chronicles Of Amber, by Roger Zelazny
Wrong. The Lord of Light!
41. The Belgariad, by David Eddings
42. The Mists Of Avalon, by Marion Zimmer Bradley
43. The Mistborn Series, by Brandon Sanderson
44. Ringworld, by Larry Niven
45. The Left Hand Of Darkness, by Ursula K. LeGuin
This comes in behind crappy fantasy series? A shame!
46. The Silmarillion, by J.R.R. Tolkien
You read this from affection for LOTR. It isn't good.
47. The Once And Future King, by T.H. White
Way underrated for a fantasy.
48. Neverwhere, by Neil Gaiman
Did anyone besides me read the novel? The TV series is good, though.
49. Childhood's End, by Arthur C. Clarke
Okay, but I'd have gone with The City and The Stars.
50. Contact, by Carl Sagan
51. The Hyperion Cantos, by Dan Simmons
52. Stardust, by Neil Gaiman
53. Cryptonomicon, by Neal Stephenson
54. World War Z, by Max Brooks
55. The Last Unicorn, by Peter S. Beagle
56. The Forever War, by Joe Haldeman
57. Small Gods, by Terry Pratchett
58. The Chronicles Of Thomas Covenant, The Unbeliever, by Stephen R. Donaldson
59. The Vorkosigan Saga, by Lois McMaster Bujold
I'd have picked Ethan of Athos if I was picking Bujold.
60. Going Postal, by Terry Pratchett
61. The Mote In God's Eye, by Larry Niven & Jerry Pournelle
62. The Sword Of Truth, by Terry Goodkind
63. The Road, by Cormac McCarthy
Is this really any good?
64. Jonathan Strange & Mr Norrell, by Susanna Clarke
The fourth fantasy that deserves to be on this list, regardless of type.
65. I Am Legend, by Richard Matheson
66. The Riftwar Saga, by Raymond E. Feist
67. The Shannara Trilogy, by Terry Brooks
68. The Conan The Barbarian Series, by R.E. Howard
69. The Farseer Trilogy, by Robin Hobb
70. The Time Traveler's Wife, by Audrey Niffenegger
71. The Way Of Kings, by Brandon Sanderson
72. A Journey To The Center Of The Earth, by Jules Verne
Do people really read these novels, or just watch the movies, then take the test?
73. The Legend Of Drizzt Series, by R.A. Salvatore
74. Old Man's War, by John Scalzi
75. The Diamond Age, by Neil Stephenson
76. Rendezvous With Rama, by Arthur C. Clarke
77. The Kushiel's Legacy Series, by Jacqueline Carey
78. The Dispossessed, by Ursula K. LeGuin
This far down the list? Scandalous!
79. Something Wicked This Way Comes, by Ray Bradbury
80. Wicked, by Gregory Maguire
81. The Malazan Book Of The Fallen Series, by Steven Erikson
82. The Eyre Affair, by Jasper Fforde
83. The Culture Series, by Iain M. Banks
84. The Crystal Cave, by Mary Stewart
85. Anathem, by Neal Stephenson
The only one of his I'd put on (aka, the one I could read.)
86. The Codex Alera Series, by Jim Butcher
87. The Book Of The New Sun, by Gene Wolfe
88. The Thrawn Trilogy, by Timothy Zahn
I'm not a literary person with refined tastes: I have read this one. And I still wouldn't put it on this list.
89. The Outlander Series, by Diana Gabaldan
90. The Elric Saga, by Michael Moorcock
Moorcock's reputation is baffling. Behold the Man was the only good thing he ever did, but Behold the Man was good enough to make this list.
91. The Illustrated Man, by Ray Bradbury
92. Sunshine, by Robin McKinley
93. A Fire Upon The Deep, by Vernor Vinge
94. The Caves Of Steel, by Isaac Asimov
95. The Mars Trilogy, by Kim Stanley Robinson
96. Lucifer's Hammer, by Larry Niven & Jerry Pournelle
97. Doomsday Book, by Connie Willis
98. Perdido Street Station, by China Mieville
99. The Xanth Series, by Piers Anthony
100. The Space Trilogy, by C.S. Lewis
Everybody likes making fun of H.G. Wells, no? Feh.
All those atrocious fantasy series, but no Mervyn Peake (Titus Groan/Gormenghast?)