Having just got a PS3 for Christmas I'm playing catch up right now, alternating between GTA IV (which is amazing, though I don't like the controls after having been conditioned to the PS2 version of driving around Liberty City in the older games - R2 just feels wrong as an accelerator and I'm forever crashing because my body keeps hitting the wrong button for the brake), and Mass Effect 2. I also have LA Noir in my queue.
In terms of games coming up, Mass Effect 3 for certain, plus I was very impressed by the previews I've seen of the reimagined Tomb Raider that's supposed to be coming out. GTA V, despite my qualms about the controls is definitely on my radar. And they recently announced a Doctor Who game that will be available on PS3 at some point, hopefully in 2012.
I expect I'll be playing more catch-up on older games in 2012 as well. Assassins Creed and sequels is top of list, and just because I count myself among those who waited years and years for it, whether it's a bad game or not I still want to at least sample Duke Nukem Forever. And first time I find Portal 2 in a discount bin, it's mine.
Alex