That's a problem with a lot of games though. I read once that the amount of gold you can carry in Minecraft, if compressed down into the 2m³ the player occupies, would have a density greater than a neutron star.I mean do we seriously believe Shepard fought her way through Saren's base on Virmire toting a dozen sets of full body armour--two of them Krogan---about fifty assorted pistols, shotguns, assault and sniper rifles plus hundreds of mods, spare omni-tools and bio-amps? Nah, me neither.
My main problem with inventories in RPGs is when they restrict how much you can carry for some reason. I played Skyrim recently, and I spent too much time managing my inventory because I ran out of room constantly. Few things in gaming are more tedious than pausing a quest to check stats on items to figure out which should be dropped. On top of that, after almost every quest I had to teleport back to my house to drop stuff off or sell it at stores. Mass Effect 1 probably had the worst inventory system I've ever encountered though, especially on console. It had such a clunky UI, and your inventory got clogged really quickly with a variety of weapons that had miniscule differences in stats. And you had to manage all that for 7 different characters.

KOTOR's inventory system was fine for me because it was limitless, I never had to waste time discarding items because I hit some arbitrary limit on what I could carry. I understand why limits exist for balance reasons, but I just consider that stuff to be wasted time.