Yeah, people often talk about what they'd love to have seen in further seasons of the show had it continued, and Azati Prime/Damage always factors into the brief musings I allow myself on the subject. It's often discussed in terms of what three more seasons could have accomplished, since TNG/DS9/VOY all pulled off seven, but realistically I think one more season would have been the unlikely final achievement for a show so low-rated as ENT.
That said, I allow myself to think of a full seven seasons on occasion, and it's broad strokes the whole way through, but broad strokes that are accentuated by Azati Prime/Damage.
What I think I would have done had I inexplicably been in charge of the show's direction is that I would have made Season 5 a sort of Season 4, Part II, since that approach was so well-received, and then I would have ended it with a big shocker: a time-skip several years into the future. I would have brought the lore forward into the opening volleys of the Romulan War, and I would have made Season 6 into a kind of Season 3, Part II with a similarly bleak direction. And I would have made sure there was another "Damage" in the running, because there'd need to be one, and because I effing love what I remember of that episode.
Season 7, for the record, would be a sort of "rising from the ashes" kind of year, in which plenty of screentime is dedicated to political establishment of the Federation. I suppose the show would have ended with that last shot from TATV, haha.
Edit: Wait, the last shot is the three ships. Before that. Wait, no. Before that is Riker's "computer, end program." Not that either.
Dammit, you know what I mean.