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These ones are milder than others that I've taken, but I think the effects can last for 3 days even though they're a daily pill- so if you're relaxing, they kick in, so when you go to do something, you feel stupid trying to do it? And then they really kick in about 2 hours after you take them. But I was so stressed from work that I couldn't eat or sleep so... something had to give. :/