Don't see nothing wrong in them suggesting a reference to it. If there's an alien girl involved at some point McCoy could say something along the lines of
"No more alien women for me, the last one I dated had spots and a big slug-thing living inside her".
Something like that would work.
Oooh... then you'd have the canon-ites saying that the Federation didn't know about the slugs until the 24th century!

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I had no idea when I first wrote my Morn post that it become as memorable as it clearly has.