Since we never got any gigaquad references in "Our Man Bashir", we can't really tell how the storing of six neural patterns from a transporter signal in a computer compares to the storing of a single live brain's synaptic patterns in a holobuffer. Perhaps the former is simply the more demanding job, there being a lot of fluff in a transporter signal?
But "Our Man Bashir" is weird to begin with. Odo claims that "this is more complicated than just an ordinary transporter pattern". No, it isn't - they are dealing with an ordinary transporter pattern, very specifically.
Yet if they only preserve the "neural signatures" (which may or may not be the same thing as "synaptic patterns") and ditch the transporter pattern for the bodies, how do they eventually restore the six heroes into their bodies? Did they just approximate some body patterns for them somehow? Surely the pattern for O'Brien's left pinky hangnail is just as intricate as that for his synapses - both are just clusters of atoms, after all. And if they can create the hangnail out of whole cloth, why not the neural signatures?
Timo Saloniemi