People smug about lack of progress fascinate me. I imagine they spend long nights reading tomes on constipation and parliamentory procedural tricks.A year later.
So carbon free fusion power would be 'on the grid in 14 years'.... we are getting there!![]()
Your proposal doesn't do anything to treat the bone marrow, where the cancerous white cells are produced nor does it prevent metastasis via other pathways. How do you propose to detect which white cells are cancerous? That is the hard part.I had this idea for a device where you pump blood into a chamber and electron beams penetrate the chamber targeting cancer cells and nuking them.
Your proposal doesn't do anything to treat the bone marrow, where the cancerous white cells are produced nor does it prevent metastasis via other pathways. How do you propose to detect which white cells are cancerous? That is the hard part.
I still want to know how you are detecting the mutated cells.Good points...... Hey it was just an idea. Well I suppose you could pump bone marrow into a similar device and target the cells there too.
I still want to know how you are detecting the mutated cells.
Current advanced research on advanced therapies uses molecular-scale targetting based on factors such as expression of anomalous proteins or even direct examination of DNA sequences for mutated segments.
Ultrasonic-guided microbead delivery of chemotherapy to tumour cells is also being trialed. That does, at least, avoid hitting all cells in the body with chemo drugs, even if it's not as advanced.
Another problem is that cancer cells evolve resistance through random variations. They are tricky buggers to pin down. The current thinking is to force resistant mutation down one pathway before applying another treatment to which the cells are extremely unlikely to be able to evolve a countermeasure.
The anomalies (proteins expressed due to mutations in the DNA) are most likely only going to be detectable at a molecular level. Let's assume the anomolous protein is expressed in the cell membrane.Ok just spitballing ideas here but there would be a database of what possible anomalies would look like or be like and an AI would help target the beams based on that database.
The anomalies (proteins expressed due to mutations in the DNA) are most likely only going to be detectable at a molecular level. Let's assume the anomolous protein is expressed in the cell membrane.
What analytical techniques are appropriate in that case? Which ones are least likely to cause cell damage on their own part? How long does it take to examine each of the billions of white blood cells? There are between 4,000 and 10,000 WBCs per microlitre of blood so between about 20 billion and 50 billion WBCs in the human body. That's a lot of cells to process, even in parallel.
Why use electron beams in preference to proton beams?
What are the probabilities of incorrect diagnosis (false negatives and positives)?
How are you dealing with the resection margin? You can't assjme that you've extracted all the cancer cells from the marrow. Surrounding blood vessels and bone might harbour some. Some bone marrow is not readily accessible. I assume you can detect the primary cancer site by looking for a "hot" area (high uptake of fluorodeoxyglucose, FDG) in a PET scan.
ETA: If the subject of advanced cancer therapies interests you, I'd suggest starting a new, dedicated thread. Otherwise, we're derailing this thread with irrelevancies.
Esse est percipi. Anyway, let's not clog up this thread.To tell the truth I hadn't really thought out every single detail. I just create ideas on the fly.
Maybe as Asbo was saying, there can be a thread about cancer treatments.Nanobots are the future for the treatment of Cancer. They can kill cancer cells one by one. The nanobots are so small that they could work at an incredible speed (almost no inertia), cancer could be eliminated in a matter of hours. The question is how do they spot the cancerous cells. Well, I've read the cancer cells are metabolically disconnected from our bodies and that means for example that they don't handle fasts very well. After a few days fast the cancer cell would appear much weaker than the normal cells. The bots would then be instructed to kill the cells that appear weaker than average, but that's only an example, I am sure doctors know of other ways to make the distinction between them.
Maybe as Asbo was saying, there can be a thread about cancer treatments.
You know what I think that's a fantastic idea. Can someone start it?
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