Speaking as someone who's a disabled wheelchair user, I've gone back and forth on this. And while I'd definitely like to see more representation on TV in general, I'm not sure about Star Trek.
Personally, I'd like to think that by the time the 23rd/24th century comes around, medicine has advanced sufficiently that disabilities are done with, or at least people have extremely viable options. Geordi's ocular implants are a great example. Today, we're probably just a few decades away from 3D-printing all sorts of internal human organs. Technology for bionic limbs has come a long way for amputees, too. By the 23rd century, in a society such as the Federation supplemented by alien tech, there should be fully-functional limb replacements and all sorts of viable gene therapies and medicines. Think about it....300 years. The difference between bloodletting and the medicine we enjoy today. So why not have the 2200's/2300's be a future in which we have a tremendous medical advantage?
There should be therapies that repair neurological abnormalities like cerebral palsy AT BIRTH. Autoimmune disorders like ankylosing spondylitis (which I have, in addition to cerebral palsy) or things like fibromyalgia that limit mobility? Gone, because immune therapies have gotten to a point where they can pinpoint where things start to go wrong in someone's body and zap it. And why should ALS still exist 300 years from now?
As cool as it would be to see someone in a Professor X-style hovering chair...again, what would be the point, especially if someone serves in Starfleet? At some point, doctors should have this stuff figured out, especially after working with and cross-referencing the medical databases of hundreds of alien worlds. Maybe Federation civilians can have "hovering chairs" but could you really serve on a starship like that? I guess you could...but to me, it would make more sense to have someone with advanced bionic limbs.
In a society like this, if disability is confronted, it could be on a certain alien world that doesn't have access to the same technology, or -- I guess -- to showcase some new disease or condition that has evolved through the years as a response to all the new therapies and gene manipulation that has occurred...or something like that.
I get that it could be empowering to see it on TV, but I've had a long time to think about this. Being disabled sucks. Personally, I'd like to imagine a future where it's gone. Cool alien gene therapies or nanites in the blood that go around repairing stuff that goes wrong in the body.
