Maybe. Someday. Don't write anything off.So, you really think they'll write a female Lex Luthor in a mainstream movie or TV show?
Remember, there's been more than one flirtation with the idea of a Gemma/Jamie Bond. And at this point, I think it's only a matter of when than if. And if James Bond isn't immune to a gender flip, then no one is.
Surely the correct way of looking at it is that there has been idle talk in the tabloids etc of a female Bond for nearly 30 years and its never happened! That's a long way from saying that it will happen, much less than it will happen for an entirely different franchise and character.