What do you think of the Planet of Titans Ent for Phase II in the art section? I've always said it was the way to go. Sleek.
I think that's a fantastic work of art, and I wouldn't be too upset if that was the hero starship. But, the scientist in me still sees a spaceship that suffers from "airliners in space syndrome." That is, the decks are parallel with the axis of motion. It'd make much more sense if the decks were perpendicular to that axis, then engine acceleration would be able to provide at least some of the ship's artificial gravity.
On the other hand, part of the charm of Star Trek is a world that abounds with super science, and trying to force it to conform to sound spaceship design according to 21st century rules would rob it of some of that charm.