Oh, boy, another Blade Runner discussion.
I'll make my usual observation: I can't imagine what it would be like to see Blade Runner for the first time in 2010. So much in the last 28 years -- movies, TV, books, video games, music, comics, advertising, you name it -- has swiped from Blade Runner that nobody can experience it now the way those of us who saw it in 1982 experienced it. Back then, there was nothing else like it, nothing else that looked or sounded like it. By now, just by absorbing basic pop culture for the last couple of decades, people have already been exposed to almost everything in it. The shock of the new that BR had in 1982 just isn't going to be there for a first time viewer now. It's going to be hard for a new viewer to get what the big deal is because they've been soaking in BR without knowing it. And, as some have mentioned, it's not an action movie. It's not a 21st century popcorn movie. Those are good things.
All of this, of course, means that anyone who considers himself or herself a science fiction movie fan needs to see Blade Runner. You may not like it, but you need to experience it.