At various points, heroes suggest destroying Stones to stop Thanos. Stark suggests sticking the Time Stone down a garbage disposal, and Vision suggests destroying the Mind Stone.
What if those Stones had been destroyed? They were the last two Thanos got, so he’d still have had the other four.
With only four Stones, Thanos couldn’t have disintegrated half the universe in a snap. But he still could have killed them slowly, planet by planet as he had done in the past. With control of four Stones, and the other two destroyed so they can’t be used against him, he’d have been too powerful to stop, wouldn’t he?
Safe to say that destroying the Time and Mind Stones happens in some of the 14,000,604 possible futures that don’t work out so well?