It's weird that Marcus/Titch's mother addressed him as "Three" in the opening flashback. At first I thought it was supposed to be some partial memory that he (or Five) experienced, mentally superimposing the "Three" name onto the reality, but it was never presented as a dream or memory, just as an omniscient-observer flashback, so substituting the name made no sense. It was also a spoiler about just who Titch was, although I guessed that from the way the opening recap was edited. (Plus One and Three were the only candidates, and One's gone.)
Nice to see the Android getting some character growth, but I feel this show does tend to fall back on cliched ideas a lot, like androids normally lacking emotion and being subject to prejudice and all these tropes we've seen before. The early first-season episodes didn't even treat the Android having emotions as an oddity or a problem; that was an idea retconned in later, apparently. And I don't like the idea that her personal growth was the result of a potential programmed into her for some mysterious reason, rather than simply an emergent property of her neural net's development or something. I'm also worried about that chip that will let her emulate human speech and behavior. I like her mannerisms just fine the way they are.
Speaking of which, I was amused by how quickly the Android said her trademark "Okay" when the handsome stubbly android asked to kiss her.
So it seems Nyx has a superpower of her own, instantly picking up physical skills, like Marvel's Taskmaster or Monica from Heroes. Is she another synthetic person like Two, or genetically enhanced? Anyway, I'd much rather see her fight-flirting with Two than Four. As for Devin, of course he has to be screwed-up too, and it turns out he's a junkie with shaky hands. Which seemed kind of a gratuitous thing to introduce, because it had zero effect on his ability operate on Six. It also feels a bit repetitive, since we went through this with Pawter on Killjoys last season (and it actually was plot-relevant there). As for Arax, I guess he's off the crew now, as I expected. And I totally guessed that Five was picking his pocket when she hugged him unexpectedly.