A good example might be the original death of the Hobogoblin in a Spider-Man/Wolverine special. Even though the character was supposed to have enhanced strength that made him able to go toe-to-toe with Spider-Man, he was still overpowered and killed by (IIRC) a group of ordinary henchmen.
This turned out to be the only plot hole that Hobgoblin creator Roger Stern needed to introduce a retcon that allowed the Hobgoblin to be REALLY revealed as the suspect that he'd originally intended (Stern had left the book before the ongoing mystery was resolved).
This turned out to be the only plot hole that Hobgoblin creator Roger Stern needed to introduce a retcon that allowed the Hobgoblin to be REALLY revealed as the suspect that he'd originally intended (Stern had left the book before the ongoing mystery was resolved).

I never thought that was the case. Vampires are superstrong and superfast, but it's not like a vampire's chest is made of iron. Anyone should be able to drive a stake through it, if they get a chance to. The problem, if you're a regular human, is just how to get into the situation where you can do it, without getting your neck snapped or bitten or killed in some other way. If, say, you somehow had a bunch of vampires chained up and unable to move and you gave the weakest human out there a stake and told them 'go and stake them', of course he/she could kill all of them.