I think The Six Million Dollar Man and The Bionic Woman, done correctly, would still be viable. SMDM would need a new title, of course, but if they went back to the original Martin Caidin novels, except make Austin an Iraq or Afghanistan vet instead of a Vietnam vet and a shuttle pilot instead of a Moon-walker, and keep with the more realistic bionics Caidin wrote about, I think it would work. Those original novels were closer to "24" than to Bigfoot.
The remake of Bionic Woman failed because the people who made it seemed to have a dislike for the original, plus they were hogtied by not licensing enough of Caidin's concepts. What they need is to go back and see what made the original work. It worked because Lindsay Wagner very much made Jaime a reluctant agent, and looked upon much of her adventures with a strong sense of irony (watching the episodes on DVD for the first time in 30 years I'm struck at how ironic that show was at times). A modern BW could work if they were able to find that balance between Chuck and Alias.
Alex