I’m an old guy, so I think I’d want a Star Trek anime to skew 1980s anime. Advanced Exploration Starship [STARSHIPNAME], the last in all caps and with that classic anime shing!-sound-and-glint when the title logo comes up. Set it somewhere post-The Undiscovered Country, during the “Monster Maroon”/industrial-looking-starships era. Our hero ship is primarily tasked with and designed for exploration of/diplomacy with non-Class-M worlds and non-humanoid aliens; instead of beaming down landing parties, our “away teams” pilot a group of specially-designed one-person exploration mecha (which may or may not fold out directly from the main ship). Maybe call them Christophers, after Shaun Jeffrey Christopher. And in the same way that several of the TOS human leads just happened to skew American, several of this show’s human leads just happen to skew Japanese.