Well. . . What I think I can say I like about this design are the aquatic references. This isn't another bird, it's actually much more like a leaping frog, about to smack down a moth. If you've ever seen a frog filmed in slo-mo, it's really a surprisingly graceful beast. It's bulbous but it's not at all hideous. And it can be sleek and mean at the same time, swift and carrying a punch.
What I think I can say I don't like about this particular design, surprisingly, is the misplaced Constitution class lower primary hull. It looks like the frog has just swallowed it, and it's hanging out of its mouth. It suggests the geometry of a different vessel which just isn't here. I can't get over how much cleaner the design looks if I just put my thumb over the lower "nipple." It looks like it could be a late 22nd century equivalent of a small submarine (maybe those sheathes could cover the bright Bussard caps when it's on silent running). There's not a lot of people manning it, probably fewer than 40, and it should have about one-third the volume of the Defiant from DS9. It should be small and not carry a lot of defensive weaponry, like shields, but instead rely on its maneuverability, stealth, and perhaps one very mean offensive weapon. (Science vessel? No way.)
But once I put my thumb down, the proportions are thrown off because that's the base of a much bigger ship that can hold several hundred people. It's hybridized at a point where it doesn't need to be hybridized; just because its primary hull is saucer-shaped doesn't mean it has to have a piece of the Constitution dangling down from it. Simply smoothed off at the bottom, this design would be killer.
DF "Down South We Got Some Mean Frogs" Scott