Spoilers Things you wish season 2 had answered.

[TedShatner10]

I wonder about the fate or state of Q Continuum and whether they're still around (or as an aftershock of Quinn's suicide they chose to migrate away from our universe or decided to die off naturally). Also Q seem immortal to us but like blackholes, even they must face a demise at the end of eternity.

And I'm puzzled how the El-Aurian a long lived (but still mortal and biological) people had a strong awareness and partial grip on Q beings.

 

[Deks]

I wonder about the fate or state of Q Continuum and whether they're still around (or as an aftershock of Quinn's suicide they chose to migrate away from our universe or decided to die off naturally). Also Q seem immortal to us but like blackholes, even they must face a demise at the end of eternity.

And I'm puzzled how the El-Aurian a long lived (but still mortal and biological) people had a strong awareness and partial grip on Q beings.

Only Q (as in this singular Q) was seemingly dying. The others seemed fine (there was in fact no mention of the Continuum dying).

Spoiler

ST: Discovery (and even though I don't like what they made of the 32nd century and how un-advanced the UFP actually is by that time frame), mentioned the Continuum wasn't in contact since sometime of the 26th century... meaning that some other Q (if not, perhaps his son) may have continued being in contact with the Federation for whatever reason until that time... after that, we don't know what happens to them.

Remember that out of all other Q, only DeLancie's Q expressed interest in UFP and Humanity. There was only that other Q in TNG who restored DeLancie's Q powers, but he didn't seem too interested in UFP and Humans like DeLancie's Q was.

Quinn interacted with them by sheer accident of VOY stumbling onto that asteroid he was confined to and arranging to have a civil discussion/hearing and eventually asylum that allowed him to commit suicide, whereas Miss Q interacted with VOY because there was a civil war in the Continuum so she went to get DeLancie's Q really (and she only cooperated with the VOY crew because she lost her powers and had no other options at her disposal - but I guess her demeanor may have changed a bit to just plain neutral after all that debacle - otherwise I don't see her as being interested in further interacting with humanity and UFP in general)... and Q's son interacted with VOY mainly because Q left him there to learn a lesson and improve his behavior initially (after which his attitude was more 'adjusted' to one that wasn't so arrogant, and he turned out to be quite the pleasant young[ish] man who told Janeway he will see her again 'soon' - and Janeway was certainly up for that).

Q's son seems like the only one who might have a good enough reason to continue interacting with the Federation after his father's death... possibly he was in contact with Janeway because she was his godmother.
If she lived until the age of 150 (or possibly older)... her death (or whatever happens to her) may be the last time the Q were in contact with the Federation - and the time frame of when the Q stopped contact with the Federation (per Disco) seems to fit that time frame (more or less).

Plus, for all we know, Janeway could have gone to the Ba'Ku planet for about 10 years to rejuvenate herself before coming back for another round... hehe (nice vacation spot if you ask me)... or some medical breakthroughs occurred which could have further extended human life expectancy to maybe 300 years (it was mentioned in 'Insurrection' that medical breakthroughs from harvesting the Ba'ku planet's radiation from the rings would double the lifespan... so if Humans already lived to 150, this could easily extend that to 300 years).

Since we know the UFP isn't the type to forcefully relocate people, they probably sent a team of scientists and established a research base/outpost to study the effects of the Ba'Ku planet's effects without harvesting its radiation and making the planet uninhabitable.... which means, the UFP could have gained the same result by just waiting a bit longer and doing proper science

But I'm sure Discovery probably decided to ignore all that... so who knows.

EDIT: I also forgot about Amanda Rogers (from TNG season 7 'True Q' episode). She and Q's son might be the only Q interested in interacting with the Federation after DeLancie's Q passing.

 

[JRob94]

Yeah, this is my big question. The death of De Lancie's Q should be a pretty big deal, not a passing "oh by the way, I am dying, you were my favorite, I have a nice life Picard."

And if Q is dying alone, that seems to imply that maybe the entire Q Continuum is dying or is already gone. Again, that should be a big deal, not something you gloss over. I feel like we should have gotten more info.

Perhaps the Q Continuum simply being so old, was at the end of his "life", kind of like a star reaching the end of his sequence. It eventually implodes into a supernova. My theory is that the big explosion at the end of finale that created the big transwarp conduit may have been the by-product of the Q Continuum disappearing. Basically, the Q Continuum disappearing created a massive vacuum in subspace which resulted in a massive implosion, which we saw the effects of in that massive release of energy and the formation of a transwarp conduit.

That makes so much sense! It’s now my headcannon as well