Spock in TOS was comfortable with who he was.
In DS9 Odo didn't grow to be more human.
Arguably Sisko grew to be less human.
Data-he followed humanity in imitation
On Voyager-I'd say you have two with the specifics being distinct-the Doctor didn't want to stop being artificial and eventually grew to appreciate who he was.
Seven was already human and has her humanity removed from her at the same time her Borg heritage wasn't something she ever fully abandoned.
And I don't recall anybody on Enterprise growing to be more human T'Pol just had issues and supposedly a Romulan father.
I didn't say all the characters were one note personalities, but many were. I actually like some of what they did with Voyagers Doctor
Spock: In TUC "Logic is the beginning of wisdom" Spock from TOS would've never said that. He grew to embrace his human side more over his lifetime
Worf: Raised by humans, & grows to accept a more human way of life than Klingon
Data: Made by a human, who failed in his previous attempt, so he made Data less human, so he could grow into it
Quark, Rom, Nog, frowned upon for being the way most greedy/self serving Ferengi are, & encouraged to be more human behaving, so much so that Nog joins Starfleet
Seven of Nine: Unlike both earlier examples of Borg being separated from the hive (Picard & Hugh) She barely seems able to wrap her head around being a fully realized indiviual soul
Tuvok & T'Pol, who I don't have any real problem with, are just more Vulcans among Starfleet character arcs, akin to Spock, which in a strange way tended to normalize the behavior much more, so they don't need to be aspiring to be more human-like, but still very "one note"
Even Garak, who I very much like, is still a variation on a one note theme, where Cardassians are supposed to be conniving & untrustworthy
I'm not saying they didn't do some interesting things with the character who has a monotype culture thing. In many cases like Garak's, They clearly did, but after so long, it was a tired trope for sure. It would've been better had they moved totally away from it at some point