Interior configuration
 
Ideally, a runabout was piloted by two crewmembers, although one pilot would suffice. (
DS9: "
The Maquis, Part I")  The pilots' consoles faced forward upon two large portholes. The  cockpit had stations for up to four crewmembers.  The two large  portholes were equipped with retractable blast shutters. (
DS9: "
One Little Ship")  Small square viewscreens mounted within the forward corners of the  cabin were used for video communication and ship status displays. (
DS9: "
Vortex") In the original configuration, a food 
replicator and a compact personnel 
transporter were located immediately behind the cockpit stations.  After the class underwent a refit as hostilities arose between the 
Federation and the 
Dominion,  the transporter and replicator were moved further back and a secondary  tactical console was positioned in the cockpit. The transporter was  capable of transporting multiple persons simultaneously. (
DS9: "
Vortex") 
 
The rear of the craft could be configured as a large crew cabin complete with sleeping and dining areas for extended travel. (
TNG: "
Timescape"; 
DS9: "
The Jem'Hadar", "
Let He Who Is Without Sin...") This area could also be used as a cargo bay. (
DS9: "
Tribunal") In  the center of the craft, between the two wing pylons, a series of  replaceable modules could be connected. These modules could be swapped  to suit mission requirements.  Examples of available modules included  science laboratories, crew quarters, and photon or quantum torpedo bays.  (
DS9: "
Melora") 
The runabout was equipped with at least one manual escape hatch, located near the front side of the vehicle. (
DS9: "
Battle Lines") A small 
Jefferies tube was also present, immediately underneath the warp core that ran along the spine of the vessel.  (
DS9: "
Blaze of Glory") 
The craft could also contain an emergency unit for 
medical emergencies. (
DS9: "
The Passenger")