I wasn't blown away, but I was intrigued enough that I will keep watching. I'll be honest and admit that if this wasn't a Joss show I'm not sure I'd stick with it. Of all of the actresses Whedon has featured on his shows, Dushku might be my least favorite--I don't think she has the range the others do. Not that she's bad, but I always found both Faith an overrated character and Dushku not especially appealing. Seeing Amy Acker only reminded me that a more interesting actress could have been the lead.
Aside from Buffy and the female characters on that show, I don't know that any of Whedon's heroines have been feminist icon types. I'm not saying that they're not strong, but they've been more traditional female characters--Cordelia and Fred were supporting characters and in more traditional roles (the empath and the smart, nerdy girl), Inara was a "companion," Kaylee an awwww shucks nerdy type and River a cypher. Again, not saying any of them were weak--none of them were--but none of them were Buffy or Willow, either.
So I didn't go into this expecting an ass kicking heroine or anything like that. I'm intrigued by the premise, but only sort of--but then, I'll be honest and admit I was only sort of intrigued by Firefly's premise. Firefly sold me pretty quickly--within a few episodes--though not immediately, so I'm willing to be patient and see where the show goes.
I admit I was hoping for slightly sharper dialogue--I realize the Whedon witticism is polarizing, but I like the smartness of it.
A Shep would fit right into this scenario, not as the victim of a dominatrix (the dominatrices are the ones in demand and who get paid after all) but as a suave gigalo type romancing rich women who are bored with their hubbies and their various straying, unreliable lovers. Some brainwashed guy who will never cheat on you or look at another woman because he can't would be immensely appealing to a lot of rich women interested in having their egos stroked by a harem of dumb, good-looking males.
I like how you think.

I'd also like to see some male dolls in sexual situations, too, if just to even things out a bit and add a little depth to the dollhouse.
I was initially turned off by the premise. My big problem was that there didn't really seem to be a main character. If Echo's kind of a blank slate and she turns into someone we ostensibly won't care about week-to-week I saw a huge problem with that. I guess Penikett's admittedly interesting FBI character is the closest we're going to get to an actual leading character.
Initially that's probably going to be the case, as well as the handler who's a former police officer. I really like Penikett and feel he's a right fit for a Whedon show.