Depression and/or crippling guilt = no soul?! This line of reasoning doesn't even track. I could actually relate a real-life story that's sort of similar to this, but it's pretty terrible. Suffice it to say, whoa.
Don't go into the psychiatric profession anytime soon.![]()
I didn't see her as depressed. Depression couldn't be instantly countered by a bad guy showing up and trying to kill everyone, well chameleon pirates stealing their deuterium.
She was just on standby, disenaged because there was nothing worthwile to hold her attention in the space desert, even such mundane tasks as "looking after her crew" and "maintaining the facilities of her starship". It was beneath her. If Kathryn didn't get to be a hero, didn't get to fight an unconquerable foe (Didn't Don Quixotee shut down when reality insisted that those windmills most certainly were not giants.) then she might as well stay in her quarters and rock back and forth.
Except that she wasn't cured by the Malon showing up. The action didn't solve any of her problems. She snapped into action and everything, but still wanted to "atone" somehow by staying behind and ensuring Voyager's safe journey through the vortex. And the crippling guilt issues were obviously still simmering deep inside well after that episode, or else Admiral Janeway wouldn't have decided to drop-kick Time in the face in the finale. She wasn't on standby simply because she had nothing to do (Chakotay implies she was still doing work, but was hiding,) she was on standby because her guilt was catching up with her. "Coda" also mentioned that she'd had problems in the past with depression.
For most of the series, we see her handling downtime just fine (although it's clearly her preference to work a lot.)
At least she isn't an attention whore . . . Or affection whore.
The series could have been much much different if she were.