Most Trek novel crossover miniseries, with the main exception of Destiny, are designed so that you can read as many or as few as you wish. As a rule, they're essentially standalone tales that simply involve the different crews dealing with different aspects of the same problem or theme. Kind of like the various Maquis-themed episodes TNG and DS9 did leading up to the Voyager pilot -- self-contained and complete on their own, but adding up to a larger arc if you see them all.
After all, the goal is to include different types of readers, not to exclude them. Some people are interested in just one or two series, while others are interested in the whole saga. So it makes sense to design crossovers to appeal to both, and to work both as individual stories and as pieces of a bigger whole.