Honestly, I admit that House's quality has slipped quite a bit over the last season or two but if Hugh Laurie is in it I'll watch it, I'd argue that no one else really "needs" to be in it. Other friends, fellows and bosses can be brought in.
Except that would undermine seven years' worth of being told that Cuddy's the only boss who can control House and Wilson's the only friend who can tolerate him.