Janeway was assimilated by a Borg cube cut off from the Collective proper due to the collapse of the transwarp network. She was then killed when the cube was destroyed. About eight months later, the collective launched a full scale invasion of the Beta Quadrant/Alpha Quadrant through a series of subspace tunnels, their goal annihalation rather than assimilation (the Federation was now considered unworthy of assimilation, too dangerous to live). Dozens of worlds were destroyed, including Deneva, Risa, Khitomer and Coridan. Qo'noS, Andor, Vulcan and Tellar were hit hard, but are intact. The invasion ended when the Caeliar- a race unknowingly involved in the original creation of the Borg- were convinced to interfere and liberate the Borg drones. The Borg are now gone, the former drones now a part of the Caeliar, who have departed. In the aftermath of the invasion, the Federation has outfitted a fleet with quantum slipstream drive (successfully used during the crisis) to go into the Delta Quadrant and confirm the Borg are truly gone. Voyager is leading the fleet. Back home, the nations of known space have been shaken by the invasion. The Gorn, Breen, Tholians, Tzenkethi, Romulan Star Empire and Kinshaya have formed a tight-knit alliance named the "Typhon Pact", having realized during the crisis there is strength in peaceful co-operation. The Federation and Klingons- rebuilding from the devestation- are tense about this, and have invited the Ferengi, Cardassians, Talarians and the breakaway Imperial Romulan State to sign the Khitomer Accords. (Oh, yeah, the Romulan Star Empire had split into two prior to the invasion, with the breakaway Imperial Romulan State led by self-proclaimed Empress Donatra, who opposes Praetor Tal'aura of the RSE (Tal'aura took power in the aftermath of "Nemesis"). The two have a personal feud as well as a political one, due to Tal'aura's execution of Donatra's lover, an admiral who attempted to remove Tal'aura from power).