You realize it's just a drawing and an old woman wasn't really cussed out, right?
I realize it's Penny Arcade, one of those things that everyone says is funny but never actually seems to be when I look at it. So my opinion in this may be a bit biased....
I feel the same way about it. Full Frontal Nerdity seems to be generally good humored and respectful, but there's something unfriendly in the atmosphere of Penny Arcade, like it's laughing at the characters rather than laughing with them.