Thanks Thrawn. I'm going to be judicious about what I pick up. I have a lot of what you had on your lists. However, I don't plan on reading Titan or Voyager with any regularity. My decision may just be based on what the back cover blurb.
As far as Titan goes, that makes sense, because the Titan novels are all standalones. Titan appears in Destiny, but those books will certainly introduce / re-introduce the character arcs you'll need within that story.
Voyager, though... definitely feel free to skip the first four, but Full Circle onward is a pretty entwined narrative, and it's also remarkably good. Most everyone on here will tell you how surprisingly outstanding Full Circle and Unworthy were; pretty much the clear highlights of 2009's schedule, even for people that never liked the VOY show at all. I'd recommend not jumping in and out of that one.