My grade: 
Average
First of all, a background of myself. BIG fan of Firefly. Not Buffy/Angel. But it was Whedon's involvement that got me to watch it tonight.
Positives...
 - An interesting idea, even if it hardly is original. But I hope that they can take the concept and run with it to some interesting places.
 - Very interesting secondary characters, in particular her handler.
Negatives:
 - T&A... Geez. I appreciate beautiful ladies, but they are really laying on thick, aren't they? Blatant demographics reach, but not in a good way. Way over the top. 
 - 
Dushku... Is just not a very good actress, or at least did not seem to be it in this episode. I had heard about her before, but this was actually the first time I have seen her in a major role  (yep, I'm not a Buffy watcher) 

. I hope she can improve, because this was not good enough to carry a whole show. And as others have pointed out, her "Echo" persona is just supremely annoying.
 - The tech geek, who is annoying and way too young to be in such a position.
I'll give this show one more episode to convince me. I'm hoping this was just an over FOX-ified pilot.