That would give 3 possibilities:
1) Khan
2) Shinzon
3) Harry Mudd
I don't necessarily agree about the human villain idea, but I think there are far more possibilities than that.
so do we think it's a good idea to harvest TOS characters for villains? you know, like they did with Khan.
also, does a Star Trek movie NEED a villain? seriously, can we do without one? why can't we have a story without any of these "Oh My GOD the Sky is Falling!" scenarios?