Well, I think that hearing almost any of McCoy's lines delivered by Daffy Duck would be fucking hilarious.
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McCoy (Daffy): I'm a doctor, not a bricklayer!
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Khan (Elmer Fudd): Where am I?
McCoy (Daffy): You're in bed, holding a knife at your doctor's throat.
Khan (Elmer): Answer my question!
McCoy (Daffy): It would be most effective if you would cut the carotid artery, just under the left ear.
Khan (Elmer): I like a brave man. Heheheheheheheh.
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McCoy (Daffy): Murderers! Assassins! You, what planet is this? No! Don't run! I won't kill you! It's they who do the killing!
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Spock (Elmer Fudd): Do not risk the ship further on my behalf.
McCoy (Daffy): Shut up, Spock! We're rescuing you!
Spock (Elmer): Why, thank you, Captain McCoy. Heheheheheh.
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McCoy (Daffy): He's dead, Jim.