"It would be exceptionally difficult for anybody to treat her. There is no magic pill that's a truth serum for a person who's a pathological liar," said Dr. Judy Kuriansky a psychologist from Columbia University, but better known from her radio show as Dr. Judy.
Kuriansky believes that Anthony likely feels that she has been rewarded for her lying with her acquittal and release from jail.
"Why would she want to go to therapy when she basically got what she wanted? There's no motivation for her to seek help," Kuriansky said. "If she had been sent to jail, maybe she would want to see somebody because her style didn't work, but it did."
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None of the psychologists who spoke with ABCNews.com have treated Casey Anthony, but spoke from observations and personal experience.
Two of the potential issues Anthony could suffer from are border personality disorder and psychopathology, the experts said. The main thing these issues have in common is a total lack of empathy, according to LeslieBeth Wish, a psychologist and licensed social worker in Sarasota, Fla.
"They can turn a person into a non-person," Wish said. "Borderline personalities have more emotional regulation problem and often use lying to get away from something and not ever feeling like they're responsible."
Wish explains that for people who suffer from these problems, separate lies can quickly become entire narratives that the teller can even come to believe as true.
"A lie begets a lie and it's easy to get trapped in telling lies to protect other lies," Wish said. "Does she believe her lies? She might, but more than likely she believes that she's good enough to make you believe her lies."