The direction of where Batman will go clearly depends on the reception that the third Nolan Batman movie gets.
Spider-Man 3 was not completely horrible, but still seen as a major step down from the second movie. So what are we getting? A reboot.
The same thing is in essence happening in the X-Men movie universe.
If Batman 3 can top the Dark Knight, Warner Brothers will keep riding the tide and try for a fourth movie in the same vein. But without Nolan it will be unlikely to succeed.
And of course it all hinges on whether or not Nolan does anything wild like killing Bruce in the 3rd movie, which has been rumored.