2x Engines are what's absolutely required due to the updated regulation for long range flight, so it's now the standard.
ETOPS - engines turning or passengers swimming

The day's of 4x Engine aircraft for Long Haul Commercial Aviation is DEAD.
2x Engines are what's absolutely required due to the updated regulation for long range flight, so it's now the standard.
The Demand for long range travel is there, ergo the A350 vs 777x and it's "High Capacity" passenger load out while using 2x engines.
QANTAS has been tooting it's horn about long distance flights but has official announced it's getting 12 A350s that will Sydney-London non-stop which is a 19 hour flight.
I suspect there's also big cost saving to do non-stop
* savings on fuel from take-off/landings/reverse thrust on landing
* landing fee costs when the aircraft has to touch for refueling and all the issues there
* saves cycles on the airframes
* allows more direct routing which increases fuel savings.
* aircraft can't stuck throwing out schedules.
On an Air Canada back flight when they used the 767s between Canada and Australia we were late out of Vancouver which made us late in Honolulul for refuel and crew change. Upon re-boarding the pilot announced we had to hustle or we'd be stuck due to curfew and we made it just in time. Had the plane been stuck it would have caused issues as it was due to fly back to Canada 4 hours after landing in Sydney.
Eliminating having to route further north to land in Hawaii, descent, ascent and time on the ground going direct saves over 2 hours on total trip time.
Oh and the biggest plus? Not having to do U.S customs.