I have not read the comics, but deviations like going to CDC can easily be explained. These events happen in the time frame between issues. From what I understand, when they left the camp they went to a gated community. As long as after leaving the CDC, they end up in a gated community and more or less the events unfold that happen in the comics you have no continuity issue with the comics.
Three problems. 1) With most of the issues, there is no passage of time between issues at all. For the most part, each issue carries on from the one directly before it. In fact, at the moment, I cannot recall a single instance where there was a passage of time between issues (though I admit my memory may be lacking, as it has been some time since I've read any issues).
2) You're simultaneously creating and trying to explain a "continuity issue" that doesn't even exist in the first place for those of us who have read the comics. We
want the show to deviate. If it doesn't, if it literally adapted only what was on the printed page, there'd be no point to adapting for television at all.
3) Shane was dead at this point in the comics. How's that for a "continuity issue"?