If Stewart wants to do this I will say this is a lock to happen! For starters we are talking about a show that will most likely be 10 to 13 episodes and Stewart might not even have to be in all of them. They can't back to the prequel setting when you already got one show on in that time and maybe more if the cartoon or Academy etc idea is done. Stewart as Picard will be a big-time drawl. TNG was popular in the day and everyone loves Patrick Stewart.
they do bring Worf back he will look funny in that new Klingon makeup though.

Maybe they can bring Data back in a different body but with Spiner doing the voice. Even though the internet would go crazy but what about a female Android looking body? RIker and Troi can show up for guests shots aboard the TItan or maybe the Enterprise since we don't even know if this show would center around a Enterprise. Crusher can call in from Starfleet Medical and Picard can spend alot of time reading Laforge's books and have him show up as well in some manner. Wesley can return as a God now that he has spent years on those other planes of experiences.
Jason