I wouldn't mind seeing a time travel plot (or one-off) focusing on the JJ-verse 24th century and seeing what effects Nero's tampering had on Captain Picard and the crew of the Enterprise-D.
Picard never left the family vineyard, but has a wonderful life drinking a bottle per day.
Riker was marooned on a desert planet by his Captain, because he tried once too many times to prevent him from going on an away mission. He was later eaten by the indigenous life forms.
Jack Crusher escaped death in this Universe, and convinced both Beverly and Wesley never to go near Starfleet again. They go through life each drinking a bottle of wine per day, supplied by Picard Vineyards.
Worf got his headbump rings caught in some farm machinery as a boy -- is now the only smooth-forehead Klingon around.
Data was never admitted to Starfleet academy, because Dean 0718 couldn't believe people in the 24th century actually thought he was advanced.
Geordi didn't pursue engineering, but instead devoted his life to teaching tribbles literature on a show called "The Reading Visible Spectrum".
Edit: almost forgot!
Enterprise D -- doesn't exist. Because the first flagship was literally decimated in every encounter it had with hostile forces, it became a bad omen to dispatch the Enterprise on a mission (not to mention cost-prohibitive to fix over and over). The name and registry were retired, never to be seen again.
Also, her first Captain (James T. Kirk) was dishonourably discharged from Starfleet once they remembered the most important attribute for a Captain was keeping his ship and crew safe.
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