Not in every case is pandering failure. But with this film I think making it an all female cast will not work.
Why?
Well I might ask the same question. Why would an all female cast work opposed to an all male one or even a mixed male and female GB crew? Even Ernie Hudson thinks it's a bad idea
http://www.oregonlive.com/movies/index.ssf/2014/10/post_58.html
I dislike reboots in general so that colors my views on this but also I grew up with Ghostbusters and it had always seemed like a boys thing because we had not only the movie but the animated series too and I can't say I remember many girls liking it. Same for Transformers or Knight-Rider.
When I see that they are going to reboot it with an female cast I think firstly it's a gimmick as a way of attracting **cough** pander **cough** to female viewers who would be less inclined to watch a continuation/soft male cast reboot because it's something from the 80s and I think the impression is that it's more of a guys film, no?
I don't know what they are going to do with the film but I don't see how an all female cast serves the story and makes it more interesting now.
Finally, I love Egon, Ray, Peter and Winston in the same way I love Kirk, Spock and Bones, Han, Leia and Luke. If they make this a hard reboot like they are claiming to then why not make it again with those same iconic male (sorry girls) characters?
We just had the 30th Anniversary celebrating this movie and these characters. Why now go for a hard reboot with an all female cast that has no connection to what we are still celebrating today? I have zero interest in that and it worries me that Paul Feig's first impression of making this work and making it funny is making it a female cast. I truly don't want this to be a dumb blonde's (male or female) farting type of comedy movie.
If it works then all the more fucking power to you. I think it won't and I'm more than happy to revisit this conversation 2 or 3 years later and see what happened with this idea.