Before I open this up to your selections, I'll snag one many of you are likely considering: Bobby Simone (Jimmy Smits) of NYPD BLUE. When it came to that show, I was more of a Dennis Franz fan. My choice of Simone is not because of his specific character, but because of the excellent five-week arc in the episodes, in the fantastic acting it brought out from his wife and colleagues (Franz in particular), and its moving conclusion in the final week. In many cases, life imitates art. Two years following these episodes, my family experienced two similar events five months apart with similar results to each other, and the show. Even before that, I knew that this would always be NYPD's absolute high point. It still is. And IMO, television's single greatest character sendoff. Your personal picks don't necessarily need to be limited to regulars, as long as you were positively moved.