And not just through biological augmentation? Supposedly, humanity was able to defeat Khan Noonien Singh and his fellow Augments, but we're not told HOW this was done. I propose that, within the context of an "arms race", various forms of human augmentation was used to defeat Khan, whether they be biological or cybernetics, and that the truth of how humanity defeated Khan was conveniently swept under the rug, for PR purposes, but being lost due to WW3. I also feel that it was this same process that enabled humanity to survive WW3's "nuclear holocaust". And, I think that Khan's dismissal of humanity's progress (as seen in TOS' "Space Seed") was more to do with his ego than any lack of progress on humanity's part. After all, Kirk was possessed genius-level intellect with an impressive military and academic record early in his career. Can't scoff at that, right?