By space vampires, do you include Borg and Wraith? If so, the lesson for space vampires is that they must be handled with care. They have great potential but become laughable so very easily.
But traditional, Dracula-style vampires in space, ech. That's just stupid.
I remember a Twilight Zone anthology novel, that had a short story where aliens have blasted the Earth to smithereens. They find some odd humans who've survived. I liked the irony of the story, vampires becoming humanity's avengers on the aliens. But generally, the traditional vampire and action of a Dracula tale doesn't work, however, with the right twist it's all right.
That was "And Not Quite Human" by Joe Hensley. It appeared in a paperback collection titled Rod Serling's Triple W: Witches, Warlocks, and Werewolves--which wasn't technically a TZ collection, but close enough.
My dad read me that story when I was a kid, and it made a lasting impression on me. In fact, I later co-edited an entire anthology of sf vampire stories titled Tomorrow Sucks.
Really.
It's out-of-print now, but, last I heard, there's a new edition in the works . . . .
Thanks for the information. That's the very book I had in high school so many ages ago. I couldn't think of the name at all, except that Rod Serling or the Twilight Zone was attached to it. 'Not Quite Human' has always been one of the most memorable vampire stories I ever read. As for when vampires lost their appeal, for me it's when they started being taken as physical beings with an explainable biology rather than metaphysical monsters. They've lost their monstrousness from having been made explicable, not just to the audience, but to the world in which they operate. They lost any sense of dread the undead should inspire.