The 3rd game in the franchise due to come out Christmas 2011 has a name and also a small teaser trailer...
I so cannot wait
[yt]http://www.youtube.com/watch?v=ZLOGh9Iixb4&feature=player_embedded[/yt]
Uncharted 3 would heavily follow the theme of deception with Nathan Drake deceiving other characters, he himself being deceived and a mysterious deception regarding Drake's ancestry.
The sequel will focus on his mentor, Victor "Sully" Sullivan, while also giving insight into how Drake is descended from the British explorer, Sir Francis Drake. The story takes place in the Arabian peninsula as Drake searches for the lost city of Iram, or as Lawrence of Arabia called it, The Atlantis of the sands

"Nathan Drake and longtime friend and mentor Victor Sullivan set off on a daring trek into the heart of the Arabian Desert. But when terrible secrets of this lost city are uncovered, their journey becomes a desperate bid for survival that will force Drake to confront his deepest fears,"
It also appears that Uncharted 3 will also follow the party line and offer a full 3D gaming experience. "Uncharted 3: Drake's Deception fully supports high-resolution Stereoscopic 3D."
I so cannot wait

[yt]http://www.youtube.com/watch?v=ZLOGh9Iixb4&feature=player_embedded[/yt]